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HIST1H2BC (Ab-20) Antibody (PACO65042)

SKU:
PACO65042
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

HIST1H2BC (Ab-20) Antibody (PACO65042)

The Hist1h2bc Polyclonal Antibody (PAC065042) is a valuable tool for researchers studying histone proteins, specifically histone H2BC. Histone H2BC is a key component of nucleosomes, the structural unit of chromatin, and plays a critical role in gene regulation and DNA packaging.This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in applications such as Western blotting and immunofluorescence. Its ability to bind to histone H2BC allows for the detection and analysis of this important histone variant in various cell types, providing insights into chromatin structure and function.

Research involving histone proteins like H2BC is essential for understanding epigenetic regulation, gene expression, and disease mechanisms. The Hist1h2bc Polyclonal Antibody can help researchers uncover the intricate roles of histone H2BC in processes such as transcriptional control, DNA repair, and cell differentiation, advancing our knowledge in fields such as cancer biology, developmental biology, and epigenetics.

Product Name:HIST1H2BC (Ab-20) Antibody
Product Code:PACO65042
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17-28aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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