Description
HIST1H2BC (Ab-15) Antibody (PACO65132)
The HIST1H2BC Antibody (PACO65132) is a reliable tool for researchers studying histone proteins and their role in chromatin organization and gene regulation. This rabbit polyclonal antibody is specifically designed to target the HIST1H2BC protein, a member of the histone H2B family known for its involvement in nucleosome structure and histone modification.This antibody is highly sensitive and has been validated for use in Western blot applications with human samples, allowing for accurate detection and analysis of HIST1H2BC expression levels in various cell types.
Researchers in the fields of epigenetics, cancer biology, and developmental biology will find this antibody to be a valuable asset in their studies.The HIST1H2BC Antibody is a valuable tool for unraveling the complexities of histone biology and its impact on gene expression and cellular function. By understanding the role of HIST1H2BC in chromatin dynamics, researchers can uncover new insights into disease mechanisms and potentially identify novel therapeutic targets for a range of human diseases.
Product Name: | HIST1H2BC (Ab-15) Antibody |
Product Code: | PACO65132 |
Size: | 50µL |
Target Names: | HIST1H2BC |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, IHC; Recommended dilution: IHC:1:10-1:100 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (9-20aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK |
Uniprot ID: | P62807 |
Background: | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Research Area: | Epigenetics and Nuclear Signaling |