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HIST1H2BC (Ab-120) Antibody (PACO65043)

SKU:
PACO65043
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
$383
Frequently bought together:

Description

HIST1H2BC (Ab-120) Antibody (PACO65043)

The HIST1H2BC Polyclonal Antibody (PAC065043) is a valuable tool for researchers studying histone H2B type 1-C/E/F/G/I, a key component of chromatin structure and gene regulation. This antibody, produced in rabbits, is highly specific to the human target and has been validated for reliable detection in Western blot applications. Its ability to bind to the histone H2B type 1-C/E/F/G/I protein allows for precise analysis and visualization in various cell types, making it an essential asset for studies in epigenetics, gene expression, and chromatin biology.

Histone H2B type 1-C/E/F/G/I is involved in packaging DNA into chromatin and plays a crucial role in regulating gene transcription and DNA replication. Dysregulation of histone H2B type 1-C/E/F/G/I has been linked to various diseases, including cancer and developmental disorders, making it a promising target for therapeutic interventions. By investigating the function and expression of this histone variant, researchers can gain valuable insights into the mechanisms underlying disease pathogenesis and potentially identify new treatment strategies.

Product Name:HIST1H2BC (Ab-120) Antibody
Product Code:PACO65043
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (112-123aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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