Description
HIST1H1B (Ab-17) Antibody (PACO65059)
Based on the information in the provided URL, the Hist1H1B (Ab-17) antibody is a polyclonal antibody that specifically targets the Histone H1.5 protein. This antibody is raised in rabbits and is highly reactive with human samples, making it a valuable tool for research in the field of epigenetics.Histone H1 proteins play a crucial role in the packaging of DNA into chromatin, and variations in their expression levels can have significant effects on gene regulation and cellular function. The Hist1H1B (Ab-17) antibody allows for the detection and analysis of Histone H1.5 protein in various cell types, providing researchers with important insights into chromatin structure and gene expression patterns.
This antibody is validated for use in Western blot applications, making it ideal for studies focusing on histone modifications and their impact on cellular processes such as transcription, DNA replication, and DNA repair. By targeting Histone H1.5, researchers can deepen their understanding of epigenetic mechanisms and their implications for health and disease.In conclusion, the Hist1H1B (Ab-17) antibody is a valuable research tool for investigating the role of Histone H1.5 in epigenetic regulation. Its high reactivity and specificity make it a reliable choice for studies exploring the complex interplay between histone proteins and gene expression.
Product Name: | HIST1H1B (Ab-17) Antibody |
Product Code: | PACO65059 |
Size: | 50µL |
Target Names: | HIST1H1B |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, IHC; Recommended dilution: IHC:1:10-1:100 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Synthesized peptide derived from Human Histone H1.5 protein (14-25aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5 |
Uniprot ID: | P16401 |
Background: | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). |
Research Area: | Epigenetics and Nuclear Signaling |