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HIST1H1B (Ab-10) Antibody (PACO65072)

SKU:
PACO65072
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

HIST1H1B (Ab-10) Antibody (PACO65072)

The Hist1h1b Polyclonal Antibody (PAC065072) is a valuable tool for researchers studying Hist1h1b, a member of the histone H1 family involved in chromatin condensation and gene expression regulation. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By targeting the Hist1h1b protein, researchers can investigate its role in various cellular processes and explore its potential implications in cancer and epigenetics research.Hist1h1b, a linker histone protein, plays a crucial role in organizing DNA into chromatin structure and influencing gene transcription.

Dysregulation of Hist1h1b expression has been linked to alterations in chromatin architecture and aberrant gene expression patterns, which can contribute to the development of diseases such as cancer and neurodegenerative disorders. By studying Hist1h1b, researchers can gain insights into the mechanisms underlying these pathological conditions and identify potential therapeutic targets for intervention.

Product Name:HIST1H1B (Ab-10) Antibody
Product Code:PACO65072
Size:50µL
Target Names:HIST1H1B
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H1.5 protein (6-17aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5
Uniprot ID:P16401
Background:Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Research Area:Epigenetics and Nuclear Signaling

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