HIRIP3 Rabbit Polyclonal Antibody (CAB7014)
- SKU:
- CAB7014
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HIRIP3 Rabbit Polyclonal Antibody |
SKU: | CAB7014 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 417-556 of human HIRIP3 (NP_003600.2). |
Sequence: | GRRG EDHP AVMR LKRY IRAC GAHR NYKK LLGS CCSH KERL SILR AELE ALGM KGTP SLGK CRAL KEQR EEAA EVAS LDVA NIIS GSGR PRRR TAWN PLGE AAPP GELY RRTL DSDE ERPR PAPP DWSH MRGI ISSD GESN |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | HIRIP3 |
Positive Sample: | HL-60,HeLa,U-937,Jurkat,Mouse skeletal muscle,Mouse liver,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8479 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |