Anti-HIPK4 Antibody (PACO23758)

Antibody Name:	HIPK4 Antibody (PACO23758)
Antibody SKU:	PACO23758
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from internal of human HIPK4.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot analysis of extracts from HUVEC cells, using HIPK4 antibody.
	Immunofluorescence analysis of A549 cells, using HIPK4 antibody.
	Immunohistochemistry analysis of paraffin-embedded human testis tissue using HIPK4 antibody.

Background:	Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter By similarity. May act as a corepressor of transcription factors Potential.
Synonyms:	Homeodomain-interacting protein kinase 4; EC 2.7.11.1; HIPK4;

UniProt Protein Function:	HIPK4: a CMGC kinase of the DYRK family.Protein type: EC 2.7.11.1; Protein kinase, CMGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CMGC group; DYRK family; HIPK subfamilyChromosomal Location of Human Ortholog: 19q13.2Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:	This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016]
UniProt Code:	Q8NE63
NCBI GenInfo Identifier:	74762559
NCBI Gene ID:	147746
NCBI Accession:	Q8NE63.1
UniProt Secondary Accession:	Q8NE63,Q96M54, A8K863
UniProt Related Accession:	Q8NE63
Molecular Weight:	69,425 Da
NCBI Full Name:	Homeodomain-interacting protein kinase 4
NCBI Synonym Full Names:	homeodomain interacting protein kinase 4
NCBI Official Symbol:	HIPK4
NCBI Official Synonym Symbols:
NCBI Protein Information:	homeodomain-interacting protein kinase 4
UniProt Protein Name:	Homeodomain-interacting protein kinase 4
UniProt Synonym Protein Names:
Protein Family:	Homeodomain-interacting protein kinase
UniProt Gene Name:	HIPK4
UniProt Entry Name:	HIPK4_HUMAN

Antibodies

Secondary Antibody