The HIP1 Polyclonal Antibody (CAB6921) is a valuable tool for researchers studying the HIP1 protein, which is involved in various cellular processes, including endocytosis and cell migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the HIP1 protein, this antibody enables the detection and analysis of HIP1 in different cell types, making it an essential reagent for studies in cell biology and cancer research.HIP1, also known as huntingtin-interacting protein 1, plays a crucial role in the regulation of cell growth and survival, making it a potential target for therapeutic interventions in cancer and other diseases.
Understanding the functions and mechanisms of HIP1 can provide insight into the development of novel treatments for cancer and other conditions associated with dysregulated cell signaling pathways. The HIP1 Polyclonal Antibody offers researchers a reliable tool for investigating the role of HIP1 in cellular processes and disease pathogenesis.
Product Name:
HIP1 Rabbit Polyclonal Antibody
SKU:
CAB6921
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-690 of human HIP1 (NP_005329.3).
The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3092
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HIP1 antibody (CAB6921) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
