The HIGD1B Polyclonal Antibody (PAC042302) is a valuable tool for researchers studying the HIGD1B protein, which plays a crucial role in mitochondrial function and cellular metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the HIGD1B protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in the fields of mitochondrial biology and metabolic research.HIGD1B, also known as HIG1 domain family member 1B, is essential for regulating cellular energy production and maintaining mitochondrial integrity.
Dysregulation of HIGD1B has been associated with various diseases, including cancer and metabolic disorders. By understanding the function of HIGD1B, researchers can gain insights into the mechanisms underlying these conditions and potentially develop targeted therapies to address them.Overall, the HIGD1B Polyclonal Antibody is a valuable tool for investigating the role of HIGD1B in cellular metabolism and mitochondrial function, with implications for a wide range of research areas, including cancer biology, metabolism, and bioenergetics.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO42302 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO42302 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
HIG1 domain family member 1B (Protein CLST 11240), HIGD1B
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the hypoxia inducible gene 1 (HIG1) domain family. The encoded protein is localized to the cell membrane and has been linked to tumorigenesis and the progression of pituitary adenomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
