HIF1β/ARNT Rabbit Monoclonal Antibody (CAB19532)
- SKU:
- CAB19532
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | HIF1β/ARNT Rabbit Monoclonal Antibody |
SKU: | CAB19532 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 499-789 of human HIF-1 beta (P27540). |
Sequence: | LAPR QQQQ QTEL DMVP GRDG LASY NHSQ VVQP VTTT GPEH SKPL EKSD GLFA QDRD PRFS EIYH NINA DQSK GISS STVP ATQQ LFSQ GNTF PPTP RPAE NFRN SGLA PPVT IVQP SASA GQML AQIS RHSN PTQG ATPT WTPT TRSG FSAQ QVAT QATA KTRT SQFG VGSF QTPS SFSS MSLP GAPT ASPG AAAY PSLT NRGS NFAP ETGQ TAGQ FQTR TAEG VGVW PQWQ GQQP HHRS SSSE QHVQ QPPA QQPG QPEV FQEM LSML GDQS NSYN NEEF PDLT MFPP FSE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta; HIF1β/ARNT |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 87kDa |
Observed MW: | 87kDa |
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 405 |
Clone Number: | ARC0010 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |