The HID1 Polyclonal Antibody (PAC019503) is a valuable tool for researchers studying the HID1 protein, a key player in cellular function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the HID1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cell signaling pathways.
HID1, also known as human increased sodium tolerance 1 protein, is essential for maintaining cellular homeostasis and function. Its role in regulating sodium levels and cellular responses to stressors makes it a promising target for research in various areas, including neuroscience, cardiovascular biology, and metabolic disorders. Understanding the function of HID1 is crucial for unlocking its potential in developing new therapeutic strategies for related diseases and conditions.
Antibody Name:
HID1 Antibody (PACO19503)
Antibody SKU:
PACO19503
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human HID1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19503(HID1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
C17orf28 (chromosome 17 open reading frame 28) is a 788 amino acid, multi-pass membrane protein that is expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. C17orf28 may be involved in the development of cancers in a broad range of tissues. Existing as three alternatively spliced isoforms, C17orf28 is encoded by a gene mapping to human chromosome 17, which makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
Synonyms:
HID1 domain containing
UniProt Protein Function:
HID1: May play an important role in the development of cancers in a broad range of tissues. Belongs to the hid-1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; DNA-bindingChromosomal Location of Human Ortholog: 17q25.1Cellular Component: cytoplasm; cytoplasmic microtubule; Golgi apparatus; Golgi medial cisterna; Golgi trans cisternaMolecular Function: protein bindingBiological Process: intracellular protein transport; response to brefeldin A
