The HIBCH Polyclonal Antibody (CAB17129) is a valuable tool for researchers studying the HIBCH protein, which is involved in a key metabolic pathway known as valine degradation. This rabbit polyclonal antibody is highly specific to human samples and is validated for use in Western blot applications.HIBCH plays a critical role in breaking down the amino acid valine, which is essential for cellular metabolism. Dysregulation of the valine degradation pathway has been linked to various metabolic disorders and diseases, making HIBCH an important target for study in fields such as metabolism, biochemistry, and genetics.
By using the HIBCH Polyclonal Antibody, researchers can detect and analyze the HIBCH protein in different cell types, providing valuable insights into its function and potential implications in disease. This antibody is a valuable tool for advancing research in metabolic pathways and understanding the role of HIBCH in health and disease.
Product Name:
HIBCH Rabbit Polyclonal Antibody
SKU:
CAB17129
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-330 of human HIBCH (NP_055177.2).
This gene encodes the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
26275
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HIBCH Rabbit pAb (CAB17129) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
