The HGFA Polyclonal Antibody (CAB10114) is a valuable tool for researchers studying the HGFA protein, a serine protease involved in various physiological processes such as blood clotting and cell migration. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications.HGFA, also known as hepatocyte growth factor activator, plays a crucial role in the activation of hepatocyte growth factor (HGF), a key regulator of cell growth, motility, and morphogenesis. Dysregulation of the HGFA-HGF axis has been implicated in various diseases, including cancer, fibrosis, and thrombosis.
By targeting HGFA with this polyclonal antibody, researchers can investigate the role of HGFA in these pathologies and potentially identify novel therapeutic targets for intervention.With its ability to specifically bind to the HGFA protein, this polyclonal antibody enables reliable detection and analysis in a variety of cell types, making it an indispensable tool for studies in molecular biology, cell biology, and disease mechanisms. Gain deeper insights into the function of HGFA and its potential as a target for therapeutic intervention with the HGFA Polyclonal Antibody (CAB10114).
Product Name:
HGFAC Rabbit Polyclonal Antibody
SKU:
CAB10114
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 408-655 of human HGFAC (NP_001519.1).
This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3083
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HGFAC antibody (CAB10114) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
