The HFM1 Polyclonal Antibody (CAB8600) is a vital tool for researchers studying the HFM1 protein, which plays a key role in DNA repair and maintenance. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications, allowing for precise detection and analysis of the HFM1 protein in various cell types.HFM1 is a crucial factor in the process of homologous recombination, a mechanism essential for the repair of DNA double-strand breaks.
Dysregulation of HFM1 has been implicated in various genetic disorders and cancers, highlighting its importance in maintaining genomic stability. Research into the functions and interactions of HFM1 is essential for understanding its role in disease development and progression, providing valuable insights for the development of targeted therapies and diagnostic tools.
Product Name:
HFM1 Rabbit Polyclonal Antibody
SKU:
CAB8600
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HFM1 (NP_001017975.4).
The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9).
Purification Method:
Affinity purification
Gene ID:
164045
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using HFM1 Rabbit pAb (CAB8600) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
