The HEY2 Polyclonal Antibody (CAB15143) is a valuable tool for researchers studying the HEY2 protein, a transcription factor involved in cellular processes such as differentiation and development. The antibody is produced in rabbits and is highly reactive with human samples, making it ideal for use in various research applications.HEY2 is known to play a critical role in regulating gene expression and cell differentiation, particularly in cardiac development and neurogenesis. Dysregulation of HEY2 has been implicated in various diseases, making it a target of interest for researchers studying cardiovascular disorders, neurodevelopmental diseases, and cancer.
This antibody is validated for use in Western blot applications, allowing for the detection and analysis of HEY2 protein in different cell types and tissues. Its specificity and high reactivity make it a reliable tool for investigating the function and regulation of HEY2 in various biological processes.
Product Name:
HEY2 Rabbit Polyclonal Antibody
SKU:
CAB15143
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1).
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
23493
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HEY2 antibody (CAB15143) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
