The HEY1 Polyclonal Antibody (CAB16110) is a high-quality research tool designed for studying the HEY1 protein, a transcription factor involved in cell differentiation and development. This antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the HEY1 protein, researchers can accurately detect and analyze its expression in various cell types.HEY1 is a key regulator of cell fate decisions and plays a vital role in embryonic development, making it a crucial target for research in developmental biology and oncology.
Its dysregulation has been linked to various diseases, including cancer and cardiovascular disorders. By understanding the function of HEY1, researchers can gain insights into its mechanisms and potential therapeutic applications.Overall, the HEY1 Polyclonal Antibody is a valuable tool for researchers studying the biological functions of HEY1 and its implications in disease pathogenesis. Its versatility and specificity make it an essential component in studies exploring the molecular mechanisms underlying cell differentiation and development.
Product Name:
HEY1 Rabbit Polyclonal Antibody
SKU:
CAB16110
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 114-129 of human HEY1 (NP_001269780.1).
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23462
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HEY1 antibody (CAB16110) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
