The HEXIM2 Polyclonal Antibody (CAB15565) is a valuable tool for research involving HEXIM2, a protein known for its role in transcriptional regulation and control of gene expression. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to the HEXIM2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it a versatile tool for studies in molecular biology and cancer research.
HEXIM2, a key player in regulating transcription elongation and RNA processing, is implicated in various cellular processes including cell growth, differentiation, and apoptosis. Its involvement in gene expression control suggests its importance in the development and progression of diseases such as cancer and neurological disorders. Research into HEXIM2 function offers insights into potential therapeutic targets for conditions with dysregulated gene expression, paving the way for innovative treatments and interventions.
Product Name:
HEXIM2 Rabbit Polyclonal Antibody
SKU:
CAB15565
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 147-286 of human HEXIM2 (NP_653209.1).
This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
124790
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HEXIM2 Rabbit pAb (CAB15565) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
