The HES6 Polyclonal Antibody (CAB16547) is a versatile tool for researchers studying the HES6 protein, a transcription factor involved in various cellular processes, including neuronal development and differentiation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications.The HES6 antibody specifically binds to the HES6 protein, allowing for precise detection and analysis in a variety of cell types. Its efficacy in immunofluorescence and immunohistochemistry assays makes it a valuable asset for studies in neuroscience, developmental biology, and cancer research.
HES6 is known for its role in regulating gene expression and cell fate determination, making it a key player in neuronal differentiation and stem cell maintenance. Understanding the function of HES6 is crucial for elucidating its impact on disease processes, such as neurodevelopmental disorders and cancer progression. This antibody provides researchers with a reliable tool for investigating the physiological and pathological roles of HES6 in various biological contexts.
Product Name:
HES6 Rabbit Polyclonal Antibody
SKU:
CAB16547
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human HES6 (NP_061115.2).
This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
55502
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using HES6 Rabbit pAb (CAB16547) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
