The HES5 Polyclonal Antibody (CAB16237) is a valuable tool for researchers studying the HES5 protein, a transcription factor that plays a key role in cell differentiation and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.HES5 is known for its involvement in regulating various cellular processes, including stem cell maintenance and neuronal differentiation. By binding to the HES5 protein, this antibody allows for the detection and analysis of HES5 expression in different cell types, making it an ideal choice for studies in developmental biology and neurobiology.
Given its importance in controlling cell fate decisions and tissue patterning, understanding the function of HES5 is essential for uncovering the mechanisms underlying development and disease. Researchers interested in exploring the role of HES5 in conditions such as neurodevelopmental disorders, cancer, and regenerative medicine will find the HES5 Polyclonal Antibody to be a valuable asset in their research endeavors.
Product Name:
HES5 Rabbit Polyclonal Antibody
SKU:
CAB16237
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human HES5 (NP_001010926.1).
Sequence:
KLLL EQEF ARHQ PNSK LEKA DILE MAVS YLKH SKAF VAAA GPKS LHQD YSEG YSWC LQEA V
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
bHLHb38; HES5
Positive Sample:
Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
18kDa
Observed MW:
18kDa
This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.
Purification Method:
Affinity purification
Gene ID:
388585
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using HES5 Rabbit pAb (CAB16237) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
