The HES2 Polyclonal Antibody (PAC061494) is a specialized tool for researchers studying HES2, a transcription factor that plays a key role in stem cell pluripotency and differentiation. This antibody, produced in rabbits, has high specificity and sensitivity for detecting HES2 in human samples and is validated for use in Western blot applications.HES2 is a critical regulator of embryonic development and cell fate determination, making it a key target for research in developmental biology and regenerative medicine. By binding to the HES2 protein, this antibody allows for precise detection and analysis in various cell types, providing valuable insight into stem cell biology and differentiation processes.
The role of HES2 in maintaining pluripotency and directing cell fate decisions makes it an essential molecule to study in the context of tissue regeneration, disease modeling, and potential therapeutic applications. By using the HES2 Polyclonal Antibody, researchers can gain a deeper understanding of the mechanisms underlying stem cell biology and pave the way for innovative advancements in regenerative medicine.
Antibody Name:
HES2 Antibody (PACO61494)
Antibody SKU:
PACO61494
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Transcription factor HES-2 protein (1-76AA)
Immunofluorescence staining of PC-3 cells with PACO61494 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Transcriptional repressor of genes that require a bHLH protein for their transcription.
Synonyms:
Transcription factor HES-2, Class B basic helix-loop-helix protein 40, bHLHb40, Hairy and enhancer of split 2, HES2, BHLHB40
UniProt Protein Function:
Transcriptional repressor of genes that require a bHLH protein for their transcription.
