Hepatitis B Core Monoclonal Antibody [PPT10E11VN] (CPAB0380)
- SKU:
- CPAB0380
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PPT10E11VN
- Applications:
- ELISA
Description
Hepatitis B Core Monoclonal Antibody [PPT10E11VN] (CPAB0380)
The Hepatitis B Core Antibody (CPAB0380) is a crucial tool for researchers studying Hepatitis B virus (HBV) infection and its impact on the immune system. This polyclonal antibody, developed using advanced technology, specifically targets the core antigen of the virus, allowing for precise detection and analysis in various experimental settings.By binding to the Hepatitis B core antigen, this antibody enables researchers to explore the mechanisms of HBV infection, replication, and pathogenesis.
Its high reactivity with human samples ensures reliable and consistent results in immunoassays such as Western blotting, ELISA, and immunohistochemistry.The Hepatitis B Core Antibody is an invaluable resource for investigating the immune response to HBV, uncovering potential therapeutic targets, and developing diagnostic tools for Hepatitis B infection. Its versatility and specificity make it an essential component of any study involving HBV and its interactions with the host immune system.
Product Name: | Hepatitis B Core antibody |
Product Sku: | CPAB0380 |
Size: | 100μg |
Host Species: | Mouse |
Immunogen: | r.HBcAg Core ayw Antigen |
Clone: | PPT10E11VN. |
Reactivity: | Viral |
Applications: | ELISA |
Purification Method: | |
Isotype: | IgG2b |
Background: | Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. |
Synonyms: | |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |