SERPIND1 Rabbit Polyclonal Antibody (CAB5848)
- SKU:
- CAB5848
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | SERPIND1 Rabbit Polyclonal Antibody |
SKU: | CAB5848 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2). |
Sequence: | GSKG PLDQ LEKG GETA QSAD PQWE QLNN KNLS MPLL PADF HKEN TVTN DWIP EGEE DDDY LDLE KIFS EDDD YIDI VDSL SVSP TDSD VSAG NILQ LFHG KSRI QRLN ILNA KFAF NLYR VLKD QVNT FDNI FIAP VGIS TAMG MISL GLKG ETHE QVHS ILHF KDFV NASS KYEI TTIH NLFR KLTH RLFR RNFG YTLR SVND LYIQ KQFP ILLD FKTK VREY YFAE AQIA DFSD PAFI SKTN NHIM KLTK GLIK DALE NIDP ATQM MIL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HC2; LS2; HCF2; HCII; HLS2; THPH10; D22S673; SERPIND1 |
Positive Sample: | U-87MG,A-431,HepG2,293T,Mouse liver,Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum lumen, extracellular exosome, extracellular region, extracellular space |
Calculated MW: | 57kDa |
Observed MW: | 57-69kDa |
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.
Purification Method: | Affinity purification |
Gene ID: | 3053 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |