UniProt Protein Function: | HEPACAM2: Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7q21.3Cellular Component: centrosome; Golgi apparatus; midbody; spindleMolecular Function: protein bindingBiological Process: centrosome organization and biogenesis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | A8MVW5 |
NCBI GenInfo Identifier: | 187659944 |
NCBI Gene ID: | 253012 |
NCBI Accession: | A8MVW5.1 |
UniProt Secondary Accession: | A8MVW5,Q6UXI0, B3KTT4, B4DPJ1, B9EG93, E9PDV5 |
UniProt Related Accession: | A8MVW5 |
Molecular Weight: | 54,115 Da |
NCBI Full Name: | HEPACAM family member 2 |
NCBI Synonym Full Names: | HEPACAM family member 2 |
NCBI Official Symbol: | HEPACAM2Â Â |
NCBI Official Synonym Symbols: | MIKIÂ Â |
NCBI Protein Information: | HEPACAM family member 2 |
UniProt Protein Name: | HEPACAM family member 2 |
UniProt Synonym Protein Names: | Mitotic kinetics regulator |
Protein Family: | HEPACAM family |
UniProt Gene Name: | HEPACAM2Â Â |
UniProt Entry Name: | HECA2_HUMAN |