The Hepacam2 Antibody (PAC027349) is a high-quality polyclonal antibody designed for research involving Hepacam2, a cell surface protein with implications in liver function and disease. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in various immunological assays, including Western blot applications. Hepacam2 is known to play a crucial role in regulating liver homeostasis and has been implicated in liver diseases such as hepatitis and liver cancer. By targeting this protein, researchers can gain valuable insights into the mechanisms underlying liver pathologies and potentially identify new therapeutic targets for liver-related disorders.
With its high reactivity and specificity, the Hepacam2 Antibody is a valuable tool for studies in hepatology and cancer research. Its ability to bind to Hepacam2 protein enables researchers to detect and analyze this important molecule in different cell types, making it an ideal choice for investigations into liver function and disease progression. By understanding the role of Hepacam2 in liver health and disease, researchers can pave the way for the development of novel treatments and interventions for liver-related conditions, ultimately improving patient outcomes and quality of life.
Antibody Name:
HEPACAM2 Antibody (PACO27349)
Antibody SKU:
PACO27349
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human HEPACAM family member 2 protein (32-351AA)
Immunohistochemistry of paraffin-embedded human liver cancer using PACO27349 at dilution of 1:100.
Background:
Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.
Synonyms:
HEPACAM family member 2 (Mitotic kinetics regulator), HEPACAM2, MIKI
UniProt Protein Function:
HEPACAM2: Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7q21.3Cellular Component: centrosome; Golgi apparatus; midbody; spindleMolecular Function: protein bindingBiological Process: centrosome organization and biogenesis
