The Hemopexin Polyclonal Antibody (CAB5603) is a crucial tool for researchers studying hemopexin, a protein involved in the regulation of heme levels in the body. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By specifically binding to the hemopexin protein, researchers can accurately detect and analyze its expression in various cell types.Hemopexin is a critical component in the body's defense against heme toxicity and plays a crucial role in heme scavenging and clearance. Research into hemopexin's functions has implications for understanding diseases related to heme imbalance, such as hemolytic anemias, sickle cell disease, and other hemoglobinopathies.
The Hemopexin Polyclonal Antibody provides researchers with a reliable tool for investigating the role of hemopexin in health and disease. Its high specificity and sensitivity make it an ideal choice for studies in hematology, biochemistry, and related fields. By elucidating the mechanisms of hemopexin action, researchers can advance our knowledge of heme metabolism and develop targeted therapies for heme-related disorders.
Product Name:
Hemopexin (HPX) Rabbit Polyclonal Antibody
SKU:
CAB5603
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-245 of human Hemopexin (Hemopexin (HPX)) (NP_000604.1).
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress.
Purification Method:
Affinity purification
Gene ID:
3263
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Hemopexin (Hemopexin (HPX)) antibody (CAB5603) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.