The Heme Oxygenase-1 Rabbit Monoclonal Antibody (CAB19062) provided by AssayGenie is a highly specific tool for researchers studying the heme oxygenase-1 protein. This antibody, generated from rabbits, exhibits superior reactivity with human samples and has been rigorously validated for use in Western blot applications. By selectively binding to the heme oxygenase-1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for investigations into cellular signaling pathways, oxidative stress, and inflammation.Heme oxygenase-1, a key enzyme in heme catabolism, plays a crucial role in maintaining cellular homeostasis by regulating oxidative stress and inflammation. Dysregulation of heme oxygenase-1 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
Therefore, studying the function and expression of heme oxygenase-1 using this antibody is essential for uncovering potential therapeutic targets and developing novel treatment strategies for these pathological conditions.Overall, the Heme Oxygenase-1 Rabbit Monoclonal Antibody (CAB19062) offered by AssayGenie is a valuable tool for researchers exploring the intricate roles of heme oxygenase-1 in health and disease. Its high specificity, reliability, and versatility make it an indispensable asset for advancing knowledge in the fields of biochemistry, pharmacology, and molecular biology.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
Purification Method:
Affinity purification
Gene ID:
3162
Clone Number:
ARC53508
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Raw264.7 cells, using [KD Validated] Heme Oxygenase 1 (HO-1/HMOX1) Rabbit mAb (CAB19062) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
