The Helicase ARIP4 Polyclonal Antibody (CAB6144) is a valuable tool for researchers studying the role of the helicase ARIP4 protein in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.Helicase ARIP4 is a crucial enzyme involved in DNA replication and repair, as well as in the regulation of gene expression. Its function in unwinding DNA structures makes it vital for maintaining genomic stability and responding to DNA damage. The Helicase ARIP4 Polyclonal Antibody enables the detection and analysis of this protein in different cell types, making it ideal for investigations in molecular biology and cancer research.
The significance of helicase ARIP4 in DNA metabolism and gene regulation highlights its potential as a target for therapeutic interventions in diseases characterized by aberrant DNA repair mechanisms, such as cancer. By studying the activity of helicase ARIP4, researchers can gain insight into the molecular pathways involved in these conditions and develop strategies for targeted treatments.
Product Name:
RAD54L2 Rabbit Polyclonal Antibody
SKU:
CAB6144
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1178-1467 of human RAD54L2 (NP_055921.2).
Predicted to enable ATP hydrolysis activity; protein kinase binding activity; and transcription coregulator activity. Predicted to be involved in DNA duplex unwinding. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nuclear speck. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
23132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAD54L2 antibody (CAB6144) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
