The HECTD1 Polyclonal Antibody (CAB9433) is a valuable tool for researchers studying HECTD1, a protein involved in the ubiquitination pathway and regulation of protein stability. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds to the HECTD1 protein, allowing for precise detection and analysis in various cell types.HECTD1 is a HECT domain-containing E3 ubiquitin ligase that plays a crucial role in protein degradation and turnover. Dysregulation of HECTD1 has been linked to various diseases, including cancer and neurodegenerative disorders.
By studying the function and activity of HECTD1, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.Overall, the HECTD1 Polyclonal Antibody is an essential tool for researchers investigating the role of HECTD1 in cellular processes and disease pathology. Its specificity and reliability make it an ideal choice for studies in molecular biology, cancer biology, and other related fields.
Product Name:
HECTD1 Rabbit Polyclonal Antibody
SKU:
CAB9433
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2518-2610 of human HECTD1 (NP_056197.3).
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in anatomical structure development; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein K63-linked ubiquitination. Predicted to act upstream of or within several processes, including animal organ development; negative regulation of protein localization to plasma membrane; and protein autoubiquitination.
Purification Method:
Affinity purification
Gene ID:
25831
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HECTD1 Rabbit pAb (CAB9433) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
