The HEBP2 Polyclonal Antibody (CAB16504) is a powerful tool for research into HEBP2, a protein involved in iron metabolism and cellular homeostasis. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in applications such as Western blotting. By binding specifically to the HEBP2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in the fields of biochemistry and molecular biology.HEBP2, also known as heme-binding protein 2, plays a crucial role in controlling the cellular levels of heme, an essential molecule for various biological processes.
Dysregulation of heme metabolism has been implicated in a range of diseases, including anemia, cancer, and neurodegenerative disorders. Research into the function of HEBP2 is vital for understanding these diseases and developing potential therapeutic strategies that target heme metabolism.By utilizing the HEBP2 Polyclonal Antibody (CAB16504), researchers can gain valuable insights into the mechanisms underlying HEBP2-mediated regulation of cellular iron homeostasis, paving the way for advancements in the diagnosis and treatment of heme-related disorders.
Product Name:
HEBP2 Rabbit Polyclonal Antibody
SKU:
CAB16504
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human HEBP2 (NP_055135.1).
The protein encoded by this gene is found predominately in the cytoplasm, where it plays a role in the collapse of mitochondrial membrane potential (MMP) prior to necrotic cell death. The encoded protein enhances outer and inner mitochondrial membrane permeabilization, especially under conditions of oxidative stress.
Purification Method:
Affinity purification
Gene ID:
23593
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HEBP2 Rabbit pAb (CAB16504) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
