The HEBP1 Polyclonal Antibody (CAB17698) is a valuable tool for researchers studying HEBP1, a protein involved in iron metabolism and mitochondrial function. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the HEBP1 protein, this antibody allows for the accurate detection and analysis of HEBP1 in various cell types, making it ideal for studies in biochemistry and cell biology.HEBP1, also known as heme-binding protein 1, plays a crucial role in the transport and utilization of iron within the mitochondria, where it is involved in heme synthesis and electron transport chain function.
Dysregulation of HEBP1 has been implicated in various diseases, including iron metabolism disorders and mitochondrial dysfunction. By studying the role of HEBP1, researchers can gain valuable insights into these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
HEBP1 Rabbit Polyclonal Antibody
SKU:
CAB17698
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human HEBP1 (NP_057071.2).
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells.
Purification Method:
Affinity purification
Gene ID:
50865
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HEBP1 Rabbit pAb (CAB17698) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
