The HEATR1 Polyclonal Antibody (CAB13102) is a valuable tool for researchers studying the HEATR1 protein, which plays a crucial role in RNA processing and cellular metabolism. This antibody, produced in rabbits, is highly specific and reacts strongly with samples from various species, making it a versatile option for a range of experimental settings.HEATR1 is a key player in RNA splicing and is essential for the proper functioning of the spliceosome, the molecular machine responsible for removing non-coding sequences from pre-mRNA. Dysregulation of RNA processing can lead to a variety of diseases, including cancer and genetic disorders.
By targeting HEATR1 with this antibody, researchers can investigate its role in cellular processes and potentially uncover new therapeutic targets for these conditions.This antibody is validated for use in Western blot applications, allowing for easy detection and analysis of HEATR1 in cell lysates. Its high specificity and sensitivity make it an excellent choice for studies in molecular biology, biochemistry, and genetics. With the HEATR1 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying RNA processing and explore new avenues for treating RNA-related diseases.
Product Name:
HEATR1 Rabbit Polyclonal Antibody
SKU:
CAB13102
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HEATR1 (NP_060542.4).
Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in fibrillar center and mitochondrion. Implicated in pancreatic ductal carcinoma. Biomarker of glioblastoma.
Purification Method:
Affinity purification
Gene ID:
55127
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using HEATR1 Rabbit pAb (CAB13102) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
