The HDGFRP2 Polyclonal Antibody (CAB7484) is a valuable tool for researchers studying HDGFRP2, a transcriptional repressor involved in cell proliferation and differentiation. This antibody, raised in rabbits, is highly specific to human samples and is suitable for use in Western blot, immunofluorescence, and immunohistochemistry applications. By targeting the HDGFRP2 protein, this antibody enables the accurate detection and analysis of HDGFRP2 expression in a variety of cell types.HDGFRP2, also known as Hepatoma-Derived Growth Factor Related Protein 2, is a key player in regulating cell growth and differentiation processes.
Its dysregulation has been implicated in various cancers and developmental disorders, making it a promising target for therapeutic interventions. Research into the functions of HDGFRP2 is essential for understanding its role in disease progression and identifying potential treatment strategies.Overall, the HDGFRP2 Polyclonal Antibody (CAB7484) provides researchers with a reliable tool for investigating the functions of HDGFRP2 in various biological contexts, offering insights that may ultimately contribute to the development of novel therapeutic approaches for cancer and other related conditions.
Product Name:
HDGFRP2 Rabbit Polyclonal Antibody
SKU:
CAB7484
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 501-670 of human HDGFRP2 (NP_116020.1).
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
84717
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse testis, using HDGFRP2 antibody (CAB7484) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
