The HDGF Polyclonal Antibody (CAB5347) is a valuable tool for researchers studying the hepatoma-derived growth factor (HDGF), a nuclear protein with pleiotropic functions in cell growth, differentiation, and tumorigenesis. This antibody, produced in rabbits, exhibits high specificity towards HDGF in human samples and is validated for use in various applications, including Western blot and immunohistochemistry.HDGF is known to play a crucial role in promoting cell proliferation, migration, and survival in various cancer types, making it a potential target for cancer therapy.
Its overexpression has been linked to poor prognosis in patients with certain malignancies, highlighting the importance of further studying its mechanisms and regulatory pathways. The HDGF Polyclonal Antibody enables researchers to investigate the expression and localization of HDGF in different cell types and tissues, providing valuable insights into its role in cancer development and progression.
Product Name:
HDGF Rabbit Polyclonal Antibody
SKU:
CAB5347
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HDGF (NP_004485.1).
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
3068
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using HDGF Rabbit pAb (CAB5347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
