The HDDC3 Polyclonal Antibody (PAC038538) is a high-quality research tool designed for studying HDDC3, a protein involved in DNA repair and genome stability. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the HDDC3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it a valuable tool for researchers in the fields of molecular biology and cancer research.HDDC3, also known as HDPAR1, plays a crucial role in maintaining genomic integrity by facilitating the repair of damaged DNA.
Dysregulation of HDDC3 has been implicated in various diseases, including cancer and neurodegenerative disorders. Therefore, studying the function of HDDC3 is essential for understanding the mechanisms underlying these conditions and developing targeted therapeutic interventions.Overall, the HDDC3 Polyclonal Antibody is a reliable resource for researchers interested in exploring the role of HDDC3 in DNA repair pathways and its potential implications for human health. Its specificity and sensitivity make it an invaluable tool for advancing scientific knowledge in the field of genomics and cancer biology.
Western blot. All lanes: HDDC3 antibody at 2µg/ml + Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 21, 16 kDa. Observed band size: 21 kDa.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO38538 at dilution of 1:100.
Background:
ppGpp hydrolyzing enzyme involved in starvation response.
HDDC3: ppGpp hydrolyzing enzyme involved in starvation response. Belongs to the MESH1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.1.7.2Chromosomal Location of Human Ortholog: 15q26.1Molecular Function: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; metal ion bindingBiological Process: metabolic process
