HDAC9 Rabbit Monoclonal Antibody (CAB2226)
- SKU:
- CAB2226
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | HDAC9 Rabbit Monoclonal Antibody |
SKU: | CAB2226 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC9 (Q9UKV0). |
Sequence: | MHSM ISSV DVKS EVPV GLEP ISPL DLRT DLRM MMPV VDPV VREK QLQQ ELLL IQQQ QQIQ KQLL IAEF QKQH ENLT RQHQ AQLQ EHIK ELLA IKQQ QELL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDAC9 |
Positive Sample: | RD,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 111kDa |
Observed MW: | 150kDa |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 9734 |
Clone Number: | ARC0735 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |