HDAC8 Rabbit Monoclonal Antibody (CAB8865)
- SKU:
- CAB8865
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | HDAC8 Rabbit Monoclonal Antibody |
SKU: | CAB8865 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC8 (Q9BY41). |
Sequence: | MEEP EEPA DSGQ SLVP VYIY SPEY VSMC DSLA KIPK RASM VHSL IEAY ALHK QMRI VKPK VASM EEMA TFHT DAYL QHLQ KVSQ EGDD DHPD SIEY GLGY |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; C8 |
Positive Sample: | 293T,HeLa,Raji,Mouse thymus,Rat brain,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 55869 |
Clone Number: | ARC1331 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |