[KO Validated] HDAC8 Rabbit Polyclonal Antibody (CAB5829)
- SKU:
- CAB5829
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | [KO Validated] HDAC8 Rabbit Polyclonal Antibody |
SKU: | CAB5829 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human HDAC8 (NP_060956.1). |
Sequence: | MEEP EEPA DSGQ SLVP VYIY SPEY VSMC DSLA KIPK RASM VHSL IEAY ALHK QMRI VKPK VASM EEMA TFHT DAYL QHLQ KVSQ EGDD DHPD SIEY GLGY DCPA TEGI FDYA AAIG GATI TAAQ CLID GMCK VAIN WSGG WHHA KKDE ASGF CYLN DAVL GILR LRRK FERI LYVD LDLH HGDG VEDA FSFT SKVM TVSL HKFS PGFF PGTG DVSD VGLG KGRY YSVN VPIQ DGIQ DEKY YQIC ESVL KEVY QAFN PKAV VLQL GADT IAGD PMCS FNMT PVGI GKCL KYIL QWQL ATLI LGGG GYNL ANTA RCWT YLTG VILG KTLS SEIP DHEF FTAY GPDY VLEI TPSC RPDR NEPH RIQQ ILNY IKGN LKHV V |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; C8 |
Positive Sample: | C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 42kDa |
Observed MW: | 45kDa |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 55869 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |