The HDAC7 Polyclonal Antibody (CAB2970) is a valuable tool for researchers studying the role of HDAC7, a histone deacetylase protein involved in epigenetic regulation and gene expression. This antibody is specifically designed for use in Western blot applications and is highly reactive with human samples.Raised in rabbits, this antibody binds specifically to HDAC7, allowing for accurate detection and analysis in a variety of cell types. Its reliability and specificity make it ideal for investigations in the fields of epigenetics, cancer research, and drug development.
HDAC7 plays a crucial role in regulating gene expression by modifying chromatin structure, making it a promising target for therapeutic interventions in cancer and other diseases. This antibody enables researchers to explore the functions of HDAC7 and its potential as a therapeutic target for various conditions.
Product Name:
HDAC7 Rabbit Polyclonal Antibody
SKU:
CAB2970
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC7 (Q8WUI4).
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51564
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using HDAC7 Rabbit pAb (CAB2970).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
