The HDAC7 Rabbit Monoclonal Antibody is a powerful tool for researchers studying the histone deacetylase 7 (HDAC7) protein, which plays a key role in epigenetic regulation and gene expression. This antibody, generated in rabbits, offers high specificity and sensitivity for detecting HDAC7 in human samples, making it ideal for use in Western blot applications.HDAC7 is a member of the histone deacetylase family, involved in the modification of chromatin structure and gene transcription. Dysregulation of HDAC7 has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
By targeting HDAC7, researchers can gain insights into its function and potential as a therapeutic target.The HDAC7 Rabbit Monoclonal Antibody enables precise detection of HDAC7 in different cell types, opening up avenues for research in areas such as epigenetics, cancer biology, and drug development. Its high specificity and reliability make it a valuable tool for understanding the role of HDAC7 in health and disease.
Product Name:
HDAC7 Rabbit Monoclonal Antibody
SKU:
CAB13008
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-198 of human HDAC7 (Q8WUI4).
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51564
Clone Number:
ARC0713
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HDAC7 Rabbit mAb (CAB13008) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
