The HDAC7 Polyclonal Antibody (CAB7285) is a valuable tool for researchers studying HDAC7, a histone deacetylase enzyme involved in gene expression regulation and cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting HDAC7 in human samples, making it suitable for Western blot analysis.HDAC7 is known to play a critical role in various biological processes, such as cell differentiation, proliferation, and apoptosis. Dysregulation of HDAC7 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. As a key player in epigenetic regulation, HDAC7 is a promising target for therapeutic interventions and drug development.
By utilizing the HDAC7 Polyclonal Antibody, researchers can gain insights into the functional role of HDAC7 in different cell types and disease contexts. This antibody enables precise detection and quantification of HDAC7 protein levels, facilitating a deeper understanding of its biological functions and potential implications for disease mechanisms. Whether studying basic cellular processes or exploring novel therapeutic targets, the HDAC7 Polyclonal Antibody is a valuable tool for advancing research in the fields of epigenetics, cancer biology, and drug discovery.
Product Name:
HDAC7 Rabbit Polyclonal Antibody
SKU:
CAB7285
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human HDAC7 (XP_011536783.1).
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51564
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HDAC7 antibody (CAB7285) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
