The HDAC7 Polyclonal Antibody (CAB16532) is a valuable tool for researchers studying the histone deacetylase 7 (HDAC7) protein, which plays a key role in epigenetic regulation and gene expression. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting HDAC7 in human samples, making it a reliable choice for Western blot applications.HDAC7 is known to be involved in various cellular processes, including cell proliferation, differentiation, and apoptosis.
Its dysregulation has been linked to cancer, cardiovascular diseases, and neurological disorders, making it a target of interest for therapeutic interventions. By utilizing the HDAC7 Polyclonal Antibody, researchers can investigate the role of HDAC7 in disease development and progression, ultimately leading to the development of new treatment strategies.
Product Name:
HDAC7 Rabbit Polyclonal Antibody
SKU:
CAB16532
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human HDAC7 (NP_056216.2).
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51564
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat pancreas using HDAC7 Rabbit pAb (CAB16532) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
