HDAC6 Rabbit Polyclonal Antibody (CAB1732)
- SKU:
- CAB1732
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | HDAC6 Rabbit Polyclonal Antibody |
SKU: | CAB1732 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HDAC6 (NP_006035.2). |
Sequence: | MTST GQDS TTTR QRRS RQNP QSPP QDSS VTSK RNIK KGAV PRSI PNLA EVKK KGKM KKLG QAME EDLI VGLQ GMDL NLEA EALA GTGL VLDE QLNE FHCL WDDS FPEG PERL HAIK EQLI QEGL LDRC VSFQ ARFA EKEE LMLV HSLE YIDL METT QYMN EGEL RVLA DTYD SVYL HPNS YSCA CLAS GSVL RLVD AVLG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HD6; JM21; CPBHM; PPP1R90; HDAC6 |
Positive Sample: | K-562,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Nucleus, Perikaryon, axon, dendrite. |
Calculated MW: | 131kDa |
Observed MW: | 160kDa |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Purification Method: | Affinity purification |
Gene ID: | 10013 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |