The HDAC6 Monoclonal Antibody is a powerful tool for researchers studying HDAC6, an enzyme involved in cell regulation and gene expression. This antibody, developed through rigorous research and validation processes, specifically targets and binds to the HDAC6 protein, allowing for precise detection and analysis in various cell types.HDAC6, a member of the histone deacetylase family, plays a key role in many cellular processes, including cell motility, protein degradation, and stress response. Dysregulation of HDAC6 has been linked to various diseases, making it a promising target for therapeutic interventions.
By utilizing the HDAC6 Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of HDAC6, paving the way for advances in drug development and personalized medicine.Whether you are conducting research in oncology, neurology, or immunology, the HDAC6 Monoclonal Antibody is a valuable tool for uncovering the role of HDAC6 in health and disease. Trust in its specificity, sensitivity, and reliability to drive your research forward and make groundbreaking discoveries in the field of molecular biology.
Product Name:
HDAC6 Monoclonal Antibody
SKU:
CAB22169
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human HDAC6 (NP_006035.2).
axon cytoplasm, caveola, centrosome, ciliary basal body, cytoplasm, cytosol, histone deacetylase complex, multivesicular body, nucleoplasm, nucleus, perinuclear region of cytoplasm
Calculated MW:
131kDa
Observed MW:
160kDa
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Purification Method:
Affinity purification
Gene ID:
10013
Clone Number:
ARC55934
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts from K-562 cells, using HDAC6 Rabbit mAb (CAB22169) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
