HDAC6 Monoclonal Antibody (CAB22169)
- SKU:
- CAB22169
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | HDAC6 Monoclonal Antibody |
SKU: | CAB22169 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human HDAC6 (NP_006035.2). |
Sequence: | NGAA VVRP PGHH AEQD AACG FCFF NSVA VAAR HAQT ISGH ALRI LIVD WDVH HGNG TQHM FEDD PSVL YVSL HRYD HGTF FPMG DEGA SSQI GRAA GTGF T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | HD6; JM21; CPBHM; PPP1R90; HDAC6 |
Positive Sample: | K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | axon cytoplasm, caveola, centrosome, ciliary basal body, cytoplasm, cytosol, histone deacetylase complex, multivesicular body, nucleoplasm, nucleus, perinuclear region of cytoplasm |
Calculated MW: | 131kDa |
Observed MW: | 160kDa |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Purification Method: | Affinity purification |
Gene ID: | 10013 |
Clone Number: | ARC55934 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |