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HDAC6 Rabbit Polyclonal Antibody (CAB11259)

SKU:
CAB11259
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
  • Autophagy Antibodies Anti-HDAC6 Antibody CAB11259
  • Autophagy Antibodies Anti-HDAC6 Antibody CAB11259
  • Autophagy Antibodies Anti-HDAC6 Antibody CAB11259
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:HDAC6 Rabbit Polyclonal Antibody
SKU:CAB11259
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 836-1104 of human HDAC6 (NP_006035.2).
Sequence:VMKV EDRE GPSS SKLV TKKA PQPA KPRL AERM TTRE KKVL EAGM GKVT SASF GEES TPGQ TNSE TAVV ALTQ DQPS EAAT GGAT LAQT ISEA AIGG AMLG QTTS EEAV GGAT PDQT TSEE TVGG AILD QTTS EDAV GGAT LGQT TSEE AVGG ATLA QTTS EAAM EGAT LDQT TSEE APGG TELI QTPL ASST DHQT PPTS PVQG TTPQ ISPS TLIG SLRT LELG SESQ GASE SQAP GEEN LLGE AAGG QDMA DSML MQGS RGLT DQAI F
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:HD6; JM21; CPBHM; PPP1R90; HDAC6
Positive Sample:Rat liver
Conjugate:Unconjugated
Cellular Localization:Cell projection, Cytoplasm, Nucleus, Perikaryon, axon, dendrite.
Calculated MW:131kDa
Observed MW:160kDa

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Purification Method:Affinity purification
Gene ID:10013
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat liver, using HDAC6 Rabbit pAb (CAB11259) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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