The HDAC2 Polyclonal Antibody (CAB13618) is a valuable tool for research involving HDAC2, a key player in epigenetic regulation and gene expression. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it an ideal choice for Western blot applications. By binding to the HDAC2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for studies in epigenetics, cancer research, and neurobiology.HDAC2, a member of the histone deacetylase family, plays a crucial role in controlling gene expression by modifying chromatin structure.
Dysregulation of HDAC2 has been implicated in various diseases, including cancer, neurological disorders, and inflammatory conditions. Understanding the function and activity of HDAC2 is essential for the development of therapies targeting epigenetic modifications in these contexts.Overall, the HDAC2 Polyclonal Antibody (CAB13618) is a reliable tool for researchers seeking to investigate the role of HDAC2 in gene regulation, disease development, and therapeutic strategies. Its high specificity and reactivity make it a valuable asset for studies aiming to unravel the complex mechanisms of epigenetic regulation.
Product Name:
HDAC2 Rabbit Polyclonal Antibody
SKU:
CAB13618
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 429-488 of human HDAC2 (NP_001518.3).
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3066
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using HDAC2 antibody (CAB13618) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
