Description
HDAC2 Monoclonal Antibody [PAT3B1AT] (CPAB0275)
The HDAC2 Polyclonal Antibody (CPAB0275) is a powerful tool for researchers studying the histone deacetylase 2 (HDAC2) protein, an important regulator of gene expression and cellular processes. This antibody, produced in rabbits, specifically targets HDAC2 in human samples and has been validated for use in Western blot applications. By binding to HDAC2, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for studies in epigenetics, cancer research, and neurobiology.
HDAC2 is known for its role in chromatin remodeling and gene transcription regulation, with implications in various disease states including cancer, neurodegenerative disorders, and inflammatory conditions. By understanding the functions and activity of HDAC2, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets. The HDAC2 Polyclonal Antibody provides researchers with a reliable tool to further explore the complex functions of HDAC2 and its impact on cellular processes.
Product Name: | HDAC2 Antibody |
Product Sku: | CPAB0275 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human HDAC2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HDAC2 amino acids 1-488 purified from Ecoli. |
Clone: | PAT3B1AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | HDAC2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | HDAC2 is a member of the histone deacetylase family that performs through the construction of large multiprotein complexes and are in charge of the deacetylation of lysine residues on the N-terminal region of the core histones. HDAC2 forms transcriptional repressor complexes by relating to a diversity of proteins, like YY1- a mammalian zinc-finger transcription factor. In addition, HDAC2 has a vital part in transcriptional regulation, cell cycle progression and developmental procedures. |
Synonyms: | Histone deacetylase 2, YAF1, HD2, YY1-associated factor 1, transcriptional regulator homolog RPD3, RPD3, EC 3.5.1.98. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |