The HDAC11 Polyclonal Antibody (CAB6140) is a valuable tool for research involving HDAC11, a histone deacetylase enzyme that plays a role in gene regulation and epigenetic modifications. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the HDAC11 protein, this antibody allows for precise detection and analysis of HDAC11 levels in various cell types, making it ideal for studies in epigenetics, gene regulation, and cancer research.
HDAC11 is a key player in the epigenetic regulation of gene expression and has been implicated in a variety of biological processes including cell differentiation, proliferation, and cell cycle progression. Research into HDAC11's role in cancer biology, inflammation, and other diseases has highlighted its potential as a therapeutic target. Understanding the function of HDAC11 is essential for developing targeted treatments that modulate gene expression and epigenetic changes associated with disease progression.
Product Name:
HDAC11 Rabbit Polyclonal Antibody
SKU:
CAB6140
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-347 of human HDAC11 (NP_079103.2).
This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
79885
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HDAC11 antibody (CAB6140) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
