| UniProt Protein Function: | MiscellaneousVariation Gly-112 is associated with low viral loads in untreated HIV patients. The level of circulating virus in the plasma of HIV patients (viral set point) varies among individuals during the nonsymptomatic phase preceding the progression to AIDS. This polymorphism explains 9.6% of the total variation in set point and is associated with the HLA-B*5701 allele, which has the strongest described protective impact on HIV disease progression. However, it is possible that HPC5 polymorphism, and not HLA-B*5701 allele, plays a direct role in the control in viremia in HIV patients. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6MZN7 |
| NCBI GenInfo Identifier: | 74709850 |
| NCBI Gene ID: | 10866 |
| NCBI Accession: | Q6MZN7.1 |
| UniProt Secondary Accession: | Q6MZN7,Q04490 |
| UniProt Related Accession: | Q6MZN7 |
| Molecular Weight: | 14,098 Da |
| NCBI Full Name: | HLA class I histocompatibility antigen protein P5 |
| NCBI Synonym Full Names: | HLA complex P5 (non-protein coding) |
| NCBI Official Symbol: | HCP5Â Â |
| NCBI Official Synonym Symbols: | P5-1; 6S2650E; D6S2650EÂ Â |
| NCBI Protein Information: | |
| UniProt Protein Name: | HLA class I histocompatibility antigen protein P5 |
| UniProt Synonym Protein Names: | HLA complex protein P5; Protein P5-1 |
| Protein Family: | HLA class I histocompatibility antigen protein |
| UniProt Gene Name: | HCP5Â Â |
| UniProt Entry Name: | |
