The HCoV-OC43 Spike S1 Monoclonal Antibody (CAB22669) is a valuable tool for researchers studying the HCoV-OC43 virus, a common human coronavirus that causes respiratory infections. This monoclonal antibody, generated in mice, specifically targets the Spike S1 protein of the virus, allowing for accurate detection and analysis in various experimental settings.The Spike S1 protein plays a crucial role in the entry of the HCoV-OC43 virus into host cells, making it a key target for antiviral drug development and vaccine research. By using this monoclonal antibody, researchers can better understand the mechanisms of viral infection and potentially develop new strategies for preventing and treating HCoV-OC43 infections.
This antibody is highly specific for the Spike S1 protein of HCoV-OC43 and has been validated for use in applications such as Western blotting and immunofluorescence. Its reactivity with human samples makes it a valuable tool for studying the interaction between the virus and host cells, providing insights that can advance our understanding of coronavirus biology and pathogenesis.
Product Name:
HCoV-OC43 Spike S1 Monoclonal Antibody
SKU:
CAB22669
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthesized peptide derived from HCoV-OC43 Spike S1.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:2000 - 1:9000
Positive Sample:
Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECDHis Tag),293F(Negative control)
Conjugate:
Unconjugated
Calculated MW:
150kDa
Observed MW:
110kDa
S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection.; [Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.
Purification Method:
Affinity purification
Gene ID:
39105218
Clone Number:
ARC57815
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HCoV-OC43 Spike S1 antibody (CAB22669) at 1:8000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
